基本信息
向明钧,男,1968年8月生,教授,博士,硕士生导师,800全讯白菜网副经理。1991年6月本科毕业于湖南800cc全讯白菜网化学系化学专业,2006年7月硕士毕业于云南老员工命科学学院动物学专业,2018年12月博士毕业于浙江大学800全讯白菜网细胞生物学专业。研究兴趣:1. 凋亡抑制蛋白 ILP-2 促进乳腺癌生长的机制;2.抑制乳腺癌等生长的民族医药研究。讲授《生物化学与分子生物学 》、《分子医学技能》等课程。主持并完成国家自然科学基金项目1项及省自然科学基金项目、省教育厅科学研究重点项目等7项,发表论文27篇(SCI论文8篇,CSCD论文6篇)。指导老员工参加“第三届全国老员工基础医学创新论坛暨实验设计大赛”获二等奖。
联系方式:xmj688@163.com (xmj688@jsu.edu.cn)
代表性成果
15.王思源1)#,向思琦2) #,王雅妮1) ,朱 林3) ,朱 柳1) ,向明钧1) * . ILP -2- ECM1 (P85)促进乳腺癌细胞的生长.中国生物化学与分子生物学报, 2019年9月35(9):996-1005
14.Mingjun Xiang, Yuting Jiang, Zhiying Hu, Yang Yang, Xiaoxue Du, Benson OA Botchway, Marong Fang.Serotonin receptors 2A and 1A modulate anxiety-like behavior in post-traumatic stress disordered mice. Am J Transl Res, 2019,11(4): 2288- 303
13.朱林,王思源,向思琦,周佩云,王雅妮,朱柳,黄慧群,向明钧*.ILP-2表达上调减轻双氧水诱导的人MCF-7细胞株凋亡.中国细胞生物学学报,2018,40(12):2051-8
12.LIN ZHU, WEIHUA ZHOU, XIDI ZHU, SIQI XIANG, SIYUAN WANG, YINGXIA PENG, BANGYUN LU,PEIZHI TANG, QIAN CHEN, MENGJUAN WU, XIA PENG, ZIYU CHEN, ZIYI SUN,KUNLIANG YANG, MINGJUN XIANG* and DANDAN YU. Inhibitor of apoptosis protein - like protein-2: A novel growth accelerator for breast cancer cells. ONCOLOGY REPORTS, 2018, 40(4): 2047-55. https://doi.org/10.3892/or.2018.6626
11.Xiang M, Jiang Y, Hu Z, Yang Y, Botchway BOA, Fang M. Stimulation of Anxiety-Like Behavior via ERK Pathway by Competitive Serotonin Receptors 2A and 1A in Post-Traumatic Stress Disordered Mice. Neurosignals. 2017 Oct 6;25(1):39-53. doi: 10.1159/000481791.Epub 2017 Oct 6
10.Wang C, Hu Z, Zou Y, Xiang M, Jiang Y, Botchway BOA, Huo X, Du X, Fang M.The post-therapeutic effect of rapamycin in mild traumatic brain-injured rats ensuing in the upregulation of autophagy and mitophagy. Cell Biol Int. 2017 Sep;41(9):1039-1047. doi: 10.1002/cbin.10820. Epub 2017 Jul 31
9.向明钧*,陈玲,李宇丹,张钰华,周佩云,刘铁军,孙远鹏,伍梦娟,方星薪,杨超萍.六溴环十二烷(HBCD)对人肝癌细胞HepG2的细胞毒性及机制.环境化学, 2016, 35(2):311-6
8.MingJun Xiang,Akhileshwar Namani,ShiJun Wu,XiaoLi Wang. Nrf2: bane or blessing in cancer? J Cancer Res Clin Oncol, 2014,140 (8):1251-9
7.向明钧,周卫华,石发宽,彭霞,朱盈姿,周佩云,伍梦娟,李宇丹,舒祖涛. 茶树花黄酮类物质抗肿瘤作用研究.食品工业科技,2013,34(12):157-60
6.Mingjun Xiang*,Wei Zhou,Dandan Gao,Xiansong Fang and Qian Liu. Inhibitor of Apoptosis Protein-Like Protein-2 as a Novel Serological Biomarker for Breast Cancer. International Journal of Molecular Sciences, 2012,13 (12):16737-50
5.向明钧,方先松,马明星,谭德勇.应用比较蛋白组学技术筛选乳腺癌血清标志物.云南大学学报(自然科学版),2011,33(4): 479-83
4.Min Yu, MingXing Ma, Chao Huang, Hui Yang, JianHua Lai, Shan Yan, Lin Li, MingJun Xiang, DeYong Tan. Correlation of Expression of Human Arrest- Defective-1 (hARD1) Protein with Breast Cancer. Cancer Investigation, 2009,27(10): 978-83
3.Min Yu,Chao Huang,Mingjun Xiang,Jianhua Lai,Hui Yang,Mingxing Ma,Deyong Tan. hARD1 Antiserum Preparation and Primary Immunohistochemical Analysis of hARD1 in Tumor Tissues.CHINESE JOURNAL OF BIOTECHNOLOGY(Online English edition of the Chinese language journal),2008,24(7):1155-61
2.向明钧,余敏,马明星,陈艳,涂源泉,谭德勇.4种不同血清样本处理方法对双向电泳效果的影响.云南大学学报(自然科学版), 2008,30(2):207-10
1.向明钧,叶金花,余敏,马明星,卑占宇,王熙才,谭德勇.血清样本双向电泳操作条件的优化.中国生物工程杂志, 2007,27(12):73-9