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宋奎导师简介

基本情况:宋奎,男,医学博士后,主任医师,800cc全讯白菜网第一附属医院大内科主任、肿瘤中心主任、血液科主任,800cc全讯白菜网临床学院内科学教研室主任,硕士生导师(内科学、生物化学与分子生物学)。第十三届湖南省人大代表,湖南省医学会理事、湖南省医师协会理事,湖南省医学会血液学分会委员。湖南省121创新人才工程第三层次、首届“武陵人才”,2020年湖南省“最美科技工作者”。主要从事血液肿瘤的靶向治疗研究。主持完成国家自然科学基金、中国博士后基金、广东省自然科学基金和湖南省自然科学基金等科研项目10余项。共发表论文60余篇,其中SCI 15篇,参编专业书籍1部。获得中山市科技进步一、二等奖各1项。

联系方式 :Email:songkui2001@163.com

代表性论文(*:通讯作者):

1. Li M, Huang TQ, Li XL, Shi ZW, Sheng Y, Hu MM,Song K*. GDC-0575, an inhibitor of CHK1, impairs the development of colitis and colitis-associated cancer by inhibiting CCR2+ macrophage infiltration in mice. OncoTargets and Therapy. 2021,14:2661-2672.

2. 李小兰,宋奎*. 骨髓衰竭性疾病患者红细胞输注疗效的临床分析. 中国输血杂志, 2021,34(5):494-497.

3. Li M,Song K,Fu SM,Huang XW,Zeng QY. Growth differentiation factor 15 prevents Lipopolysaccharide- and D-galactosamine-induced inflammation and acute liver injury in mice. International Journal of Molecular Medicine. 2018, 42(3):1756-1764.

4. 李小兰,宋奎*. 过敏性紫癜的发病机理研究. 医学检验与临床,2018, 29(12):39-42.

5. Song K,Li M,Xu XJ,Xuan L,Huang GN,Liu QF. Resistance tochemotherapy is associated withaltered glucose metabolism inacute myeloid leukemia.Oncology Letters, 2016, 12(1):334-342.

6. Song K, Li WC, Li M. Acutepromyelocyticleukemiafollowing autologous bone marrow derived mesenchymal stem cells transplantation for traumatic brain injury.Oncology Letters, 2015, 10(5):2905-2908.

7. Song K, Xu XJ, Li M.Hypocellular MyelodysplasticSyndromewithMyelofibrosis in Acute Myeloid Leukemia Transformation:a Case Report.Oncology Letters, 2015, 10(1):

422-424.

8. Song K,Li M. BuddChiari syndrome, a rare complication of multicentric Castleman disease: A case report. Oncology Letters,2015, 9(5):2153-2159.

9. Song K,Li M.Pregnancy-induced Hypertension Caused by All-Trans Retinoic Acid Treatment in Acute Promyelocytic Leukemia. Oncology Letters, 2015, 10(1):364-366.

10.宋奎,黎敏,许晓军,刘启发.能量代谢异常在慢性粒细胞性白血病伊马替尼耐药中的研究.广东医学,2015, 36(21):3318-3321.

11.宋奎,许晓军,郭子文,黎伟超,黄贵年,林淑华,刘安梨.造血干细胞移植患者血小板输注疗效的临床观察.广东医学,2014,35(21):3393-3395.

12.Song K,Li M,Xu XJ,Xuan L,Huang GN,Song XL,Liu QF. HIF-1α and GLUT1 Gene Expression is Associated with Chemoresistance of Acute Myeloid Leukemia.Asian Pac J Cancer Prev. 2014;15(4):1823-1829.

13. 宋奎,许晓军. 糖酵解与血液肿瘤. 中华医学杂志,2012,92(22):1576-1578.

14. 宋奎,许晓军. 肿瘤细胞的糖酵解能量代谢机制. 中国肿瘤临床,2012,39(16):1239-1242.

15.Jiang GB,Lin ZT,Xu XJ, Zhang H,Song K*. Stable nanomicelles base on chitosan derivative: in vitro antiplatelet aggregation and adhesion properties.Carbohydrate Polymers, 2012,88(1):232-238.

16.宋奎,许晓军,郭子文,何慧清,邱大发,黄贵年,林淑华,刘安梨,刘启发. 血液输注与脱离输血依赖在异基因造血干细胞移植中的研究.广东医学,2012,33(3):344-346.

17.宋奎,许晓军,黄贵年,郭子文,何慧清,刘启发.全反式维甲酸治疗相关分化综合征的发生与治疗情况分析.实用医学杂志,2011,27(24):136-138.

18.包陆君,高宜录,王君宇,宋奎*. Vimentin在人脑胶质瘤中表达及临床意义.广东医学,2011,32(24):3216-3219.

19.Lin ZT,Song K, Bin JP, Liao YL, Jiang GB.Characterization of polymer micelles withhemocompatibility based onN-succinyl chtiosan grafting with long chain hydrophobic groups and loading aspirin. Journal of material chemistry.2011, 21 (47):19153 – 19165.

20.Xin ZT, Carroll KA, Kumar N,Song K, Ly H. Transcriptional Activation of TINF2, a Gene Encoding the Telomere-Associated Protein TIN2, by Sp1 and NF-kB Factors. PLoS One. 2011;6(6):e21333.

21.黄贵年,林东军,许晓军,郭子文,何慧清,邱大发,林淑华,宋奎*.急性早幼粒细胞性白血病患者全反式维甲酸治疗相关分化综合征.广东医学,2011,32 (9):1129-1131.

22.宋奎,邱大发,郭子文,何慧清,简黎,黄贵年,黄桂英,刘安棃,许晓军.输血支持在造血干细胞移植中的研究.中国组织工程研究与临床康复, 2011,15

(19):3513-3517.

23.宋奎,郭子文,何慧清,简黎,邱大发,黄贵年,林淑华,任志娟,黎伟超,刘安棃,许晓军.造血干细胞移植与血小板输注.中国组织工程研究与临床康复, 2011,15(14):2567-2571.

24.宋奎,许晓军,陈方平.糖基化磷脂酰肌醇特异性磷脂酶D对白血病细胞粘附和侵袭功能的影响及机制.实用医学杂志,2011,27(8):1341-1344.

25.宋奎,许晓军,黄贵年,郭子文,林淑华,何慧清,邱大发,刘启发.73例急性早幼粒细胞性白血病患者临床特点和预后分析.广东医学,2011,32(5):635-637.

26.宋奎,许晓军,黄贵年,郭子文,何慧清,林淑华,任志娟,黎伟超,邱大发,刘启发.全反式维甲酸联合高三尖杉酯碱治疗急性早幼粒细胞性白血病的临床研究.实用临床医药杂志,2011,15(1):46-49.

27.宋奎,许晓军,陈方平.糖基化磷脂酰肌醇特异性脂酶D的表达与白血病细胞粘附和侵袭性的研究.广东医学,2011,32(2):154-157.

28.Song K, Sun XJ, Wang J, Zhou SJ, Zeng H, Chen FP. Role of glycosylphosphatidylinositol-specific phospholipase D in the homing of umbilical cord blood, mobilized peripheral blood and bone marrow-derived hematopoietic stem/progenitor cells. Leukemia Research. 2007, 31(12):1701- 1707.

29.Xin HY, Jiang DJ, Jia SJ,Song K, Wang GP, Li YJ, Chen FP. Regulation by DDAH/ADMA pathway of lipopolysaccharide-induced tissue factor expression in endothelial cells. Thrombosis and Haemostasis, 2007, 97(5):830-838.

30.Song K, Sun XJ, Wang J, Chen FP. How Glycosylphosphatidylinositol-phospholipase D acts in homing of hematopoietic stem/progenitor cells? Medical Hypotheses, 2007, 69(3):660-665.

31.宋奎,陈方平,周淑娟,赵谢兰,何群,舒毅刚,吴登蜀,付斌,刘弋. 186例

血液病患者血小板输注临床分析.临床血液学杂志, 2007, 20(3):167-170.

32.宋奎,周淑娟,曾辉,何群,舒毅刚,吴登蜀,赵谢兰,付敢,陈方平.血液病

患者预防性血小板输注阈值的依从性研究.实用医学杂志, 2007, 23(2):

277-279.

33.宋奎,陈方平,舒毅刚,李晓林.青年慢性中性粒细胞性白血病1例. 实用医学杂志, 2006, 22(10):1224.

34.Zeng H, Wang H, Chen FP, Xin HY, Wang GP, Xiao L,Song K, Wu DS, He Q, Shen GL. Development of quartz-crystal-microbalance-based immunosensor array for clinical immunophenotyping of acute leukemias. Analytical Biochemistry, 2006, 351(1):69-76.

35.宋奎,何群.抗氧化剂An7845对K562白血病细胞的增殖抑制和凋亡诱导活性.中南大学学报(医学版), 2004, 29(3):257-260.

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